New Developments in Coagulation Analyzing

Morayma ReyesA July 28th press release from Siemens Healthcare Diagnostics introduced their newest development for fast and reliable testing at the point of care: a portable coagulation analyser.

Similar in size to a smartphone and weighing 300g, the Xprecia Stride Coagulation Analyser is a hand-held and portable coagulation analyser that’s able to deliver fast, reliable testing in any clinical environment.

Launched by Siemens Healthcare Diagnostics, it’s used for prothrombin time testing (PT/INR) for point-of-care monitoring and management of oral anticoagulation therapy (OAT) with warfarin, which is a vitamin K antagonist, the Xprecia Stride was specifically designed to meet the increasing demand for speedy and reliable PT/INR results to help clinicians make accelerated and confident decisions.

Part of therapy monitoring for patients with a myriad of conditions including atrial fibrillation, open and minimally invasive heart valve replacement, deep vein thrombosis, and congenital heart defects, PT/INR tests provided by Xprecia Stride are “designed to be safe and efficient whilst allowing many patients to be tested in a broad variety of environments,” said Steve Carey, Product Manager Point of Care at Siemens Healthcare Diagnostics.

Carey claims the Xprecia Stride to be one of the most user-friendly designed point-of-care coagulation analysers since they became available over two decades ago. With it’s very user-friendly interface featuring simplistic icons and animation, it can be held at a variety of angles to ensure efficient and comfortable blood sampling when brought directly to the patient’s finger.

For even more efficiency, an integrated bar-code scanner simplifies data capture for identification of operator and patient plus accurate calibration of new lot numbers prior to testing. Results are processed within seconds of use, utilising the same reagent used by Siemens central laboratory analysers to minimise any potential for variability.

Allowing easy data transfer to computers, a color display, animated step-by-step instructions to help guide the user, and safety features that allow users to eject a used test strip and easily dispose of it without ever touching it, it’s no wonder the Xprecia Stride is the recipient of the internationally respected Red Dot Award: Product Design for 2015.

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Understanding and Monitoring Bleeding Disorders

Dr. Morayma ReyesBleeding disorders affect millions of people across the world annually. Many people who suffer from these conditions have problems with blood clotting and coagulation, or hemophilia- a disease that is mostly found in males. The roots to these disorders could be hereditary, or due to inactivity and dietary restrictions. There are levels of severity to coagulation, which is why doctors encourage patients with a family history of this disease to undergo tests in order to closely monitor this disorder. 

Most of the tests are administered in hospital safe environments and do not require any preparation from patients. These tests are meant to evaluate organs that are closely related to coagulation disorders such as the liver and the reduction of coagulation factors in the blood stream. Identifying problems within these factors like the activity levels within the blood stream can aid physicians to find the root problem and establish an appropriate treatment.

The testing is meant to discover if the patient is able to control their blood clotting process by administering enough coagulation activity. If doctors determine that the factors are too low or non existent, then the disorder is associated with a lower clot formation and bleeding. In other cases, patients that have a high amount of clot formations are usually associated with thrombosis- a disorder that obstructs the blood flow though veins.

A few indicators that can impel patients to seek out tests could be the experience of bruising easily, excessive bleeding and extended Prothrombin Time (PT) or Partial Thromboplastin Time (PTT). In many cases, patients who are experiencing low levels of vitamin K deficiency, or liver disease are also encouraged to get tested.